کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2839068 1165081 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Emerging biology of vascular wall progenitor cells in health and disease
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی پزشکی مولکولی
پیش نمایش صفحه اول مقاله
Emerging biology of vascular wall progenitor cells in health and disease
چکیده انگلیسی

New blood vessels are formed through angiogenesis and postnatal vasculogenesis. Thus, it is essential to identify vascular stem and progenitor cell niches and the mechanisms governing their role in blood vessel formation. Although much is known about circulating and bone marrow-derived endothelial progenitor cells (EPCs), little is known about the vascular wall as an EPC niche. Experimental evidence strongly suggests that EPCs, as well as other stem and progenitor cells, reside in distinct zones of the vessel wall, such as within the subendothelial space and in the so-called “vasculogenic zone” within the vascular adventitia. In this review, we discuss the potential implications of different types of vascular wall resident stem and progenitor cells in health and disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 15, Issue 11, November 2009, Pages 501–509
نویسندگان
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