کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2847044 1571336 2014 5 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
Airflow obstruction and left ventricular filling pressure in suspected chronic obstructive pulmonary disease
ترجمه فارسی عنوان
انسداد جریان هوا و فشار پرشده بطن چپ در بیماری های مزمن انسدادی مزمن ریوی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
چکیده انگلیسی


• Airflow obstruction is related to reduced left ventricular end-diastolic volume, stroke volume, and cardiac output.
• Forty-seven individuals with suspected chronic obstructive pulmonary disease (COPD) underwent pulmonary function tests and echocardiography.
• We demonstrated that airflow obstruction inversely predicts left ventricular filling pressure in suspected COPD cases.

Left ventricular (LV) filling impairment is present in patients with chronic obstructive pulmonary disease (COPD). Airflow obstruction is related to reduced LV end-diastolic volume, stroke volume, and cardiac output. The ratio of peak early diastolic filling velocity of the mitral inflow to peak early diastolic velocity of the mitral annulus (E/e′), an echocardiographic parameter, can be applied as a surrogate marker of LV filling pressures. Forty-seven individuals with suspected COPD underwent pulmonary function tests and echocardiography. The ratio of forced expiratory volume in 1 s to forced vital capacity (FEV1/FVC) and the E/e′ ratio were determined. Multivariate linear regression analysis showed that the FEV1/FVC ratio (β = 0.01; 95% confidence interval, 0.001–0.019; p = 0.036) independently predicted the log transformed E/e′ ratio. An increase of FEV1/FVC ratio (in percentage) by 1 unit was associated with an increase of the E/e′ ratio multiplied by 1.01. Airflow obstruction inversely predicts LV filling pressure in suspected COPD cases.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 192, 1 February 2014, Pages 85–89
نویسندگان
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