کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2847075 | 1571335 | 2014 | 7 صفحه PDF | دانلود رایگان |

A new analysis of the relationship between cardiac output (Q˙) and oxygen consumption (V˙O2) is presented (Q˙−V˙O2 diagram). Data from different sources in the literature have been used for validation in three conditions: exercise and rest in normoxia, and exercise in hypoxia. The effects of changes in arterial oxygen concentration (CaO2)(CaO2) on Q˙ are discussed, as well as the effects of predominant sympathetic or vagal stimulation. Differences appear depending on whether CaO2CaO2 is varied by means of changes in blood haemoglobin concentration or changes in arterial oxygen saturation. The present Q˙−V˙O2 diagram allows comprehensive description of oxygen transport in exercising humans; it expands applicability of the historical Q˙−V˙O2 relationship to include CaO2CaO2 variations; it opens new pathways for understanding underlying mechanisms; it allows computation of Q˙ from CaO2CaO2 and V˙O2 measurements, when Q˙ cannot be measured.
Journal: Respiratory Physiology & Neurobiology - Volume 193, 1 March 2014, Pages 55–61