کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2847769 1571346 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antenatal environmental stress and maturation of the breathing control, experimental data
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
پیش نمایش صفحه اول مقاله
Antenatal environmental stress and maturation of the breathing control, experimental data
چکیده انگلیسی

The nervous respiratory system undergoes postnatal maturation and yet still must be functional at birth. Any antenatal suboptimal environment could upset either its building prenatally and/or its maturation after birth. Here, we would like to briefly summarize some of the major stresses leading to clinical postnatal respiratory dysfunction that can occur during pregnancy, we then relate them to experimental models that have been developed in order to better understand the underlying mechanisms implicated in the respiratory dysfunctions observed in neonatal care units. Four sections are aimed to review our current knowledge based on experimental data. The first will deal with the metabolic factors such as oxygen and glucose, the second with consumption of psychotropic substances (nicotine, cocaine, alcohol, morphine, cannabis and caffeine), the third with psychoactive molecules commonly consumed by pregnant women within a therapeutic context and/or delivered to premature neonates in critical care units (benzodiazepine, caffeine). In the fourth section, we take into account care protocols involving extended maternal–infant separation due to isolation in incubators. The effects of this stress potentially adds to those previously described.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 168, Issues 1–2, 31 August 2009, Pages 92–100
نویسندگان
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