کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2848442 1167422 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Investigations in subjects with cough following upper respiratory tract infection
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
پیش نمایش صفحه اول مقاله
Investigations in subjects with cough following upper respiratory tract infection
چکیده انگلیسی

The study aimed to investigate subjects with cough following acute upper respiratory tract infection (URTI), and to compare those subjects unable to suppress cough (“non-suppressors”) with those who were able to suppress cough (“suppressors”). Forty-three URTI subjects participated, 31 with cough associated with acute URTI and 12 healthy controls; 21 of the coughing subjects were “suppressors”, 10 were “non-suppressors”. We obtained responses to chemical and mechanical stimulation of the nasal cavity or the pharynx using both psychophysical measures and event-related potentials. The study provided the following results: (1) “non-suppressors” did not exhibit significantly different intensity ratings or event-related potentials in comparison to “suppressors” in terms of responses to intranasal irritant, mechanical, or olfactory stimuli; (2) when pharyngeal mechanical stimuli were investigated “suppressors” rated the stimuli as more intense than “non-suppressors” and controls; (3) latencies of event-related potentials to pharyngeal stimuli were longest in “non-suppressors”. Keeping in mind the relatively small sample size, it appears possible to differentiate certain types of cough during uncomplicated URTI. This may help to explain interindividual differences in responsiveness to cough medication.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 156, Issue 1, 16 April 2007, Pages 79–84
نویسندگان
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