کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2848504 | 1167426 | 2007 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Exercise-induced depression of the diaphragm motor evoked potential is not affected by non-invasive ventilation
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
فیزیولوژی
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چکیده انگلیسی
Whole body exercise is followed by a depression of the diaphragm motor evoked potential (MEP). It is unknown whether the change is due to diaphragm activity or whole body exercise. To test the hypothesis that exercise-induced MEP depression was related to diaphragm activity, we performed two experiments. The first examined the effect of whole body exercise, performed with and without the use of non-invasive ventilation (NIV). NIV resulted in significant unloading of the diaphragm (pressure time product 101 ± 68 cm H2O/s/min versus 278  ±  95 cm H2O/s/min, p < 0.001). Both conditions produced significant MEP depression compared to the control condition (% drop at 5 min, after exercise and exercise with NIV: 29 and 34%, p = 0.77). Study 2 compared exercise with isocapnic hyperventilation. At 20 min the MEP had fallen by 29% in the exercise session versus 5% with hyperventilation (p = 0.098). We conclude that the work of breathing during whole body exercise is not the primary driver of exercise-induced diaphragm MEP depression.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 155, Issue 3, 15 March 2007, Pages 243-254
Journal: Respiratory Physiology & Neurobiology - Volume 155, Issue 3, 15 March 2007, Pages 243-254
نویسندگان
Mark J. Dayer, Sophie Jonville, Michelle Chatwin, Elisabeth B. Swallow, Raphael Porcher, Tarek Sharshar, Ewen T. Ross, Nicholas S. Hopkinson, John Moxham, Michael I. Polkey,