کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
303542 | 512746 | 2012 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Simulation of red blood cell motion in microvessels using modified moving particle semi-implicit method Simulation of red blood cell motion in microvessels using modified moving particle semi-implicit method](/preview/png/303542.png)
Red Blood Cells (RBCs) are the main cells in human blood, with a main role in the mechanical properties of blood as a fluid. Several methods have been improved to simulate the mechanical behavior of RBC in micro-capillaries. Since, in microscopic scales, using discrete models is more preferred than continuum methods, the Moving Particle Semi-Implicit method (MPS), which is a recent innovative particle based method, can simulate micro-fluidic flows based on Navier–Stokes equations. Although, by recent developments, the MPS method has turned into a considerable tool for modeling blood flow in micro meter dimensions, some problems, such as a commitment to use small time step sizes, still restrict the method for large models and also for long time simulations. A new modified semi-implicit algorithm is developed and implemented on RBC motion through microvessels, in order to reduce calculation time by more than a factor of twenty, while the error of position and velocity remains constant. A two-dimensional, parallel plate, fluid flow is simulated based on the proposed method, and the effect of the calculation time decrement is evaluated. Findings indicate a reduction of 90 percent in simulation time compared to previous studies with the same results. This significant developed method could be applied to RBC interaction within micro-capillaries and constricted zones in blood flow.
Journal: Scientia Iranica - Volume 19, Issue 1, February 2012, Pages 113–118