کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
303602 512748 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Solubilities of acetaminophen in supercritical carbon dioxide with and without menthol cosolvent: Measurement and correlation
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی عمران و سازه
پیش نمایش صفحه اول مقاله
Solubilities of acetaminophen in supercritical carbon dioxide with and without menthol cosolvent: Measurement and correlation
چکیده انگلیسی

The solubility of acetaminophen in SuperCritical-Carbon Dioxide (SC- CO2) with and without menthol as a cosolvent was measured at various temperatures (313, 328 and 343) K, and within pressures ranging from (10 to 25) MPa. It should be stated that the cosolvent, menthol, has chiral isomers with different melting points. Therefore, the effects of both menthol (I) with a lower melting point and menthol (II) with a higher melting point, as cosolvents on the solubility of acetaminophen in SC- CO2, were studied. The experimental data collected in this work were obtained using a static flow apparatus. The experiments were replicated at least three times and the data reported are the average of the replicas. Finally, the data reduction for the solubility of acetaminophen in SC- CO2 in the presence and in the absence of menthol (I) and menthol (II), were correlated, using the semi-empirical equations proposed by Chrastil and Mendez-Santiago & Teja. The results obtained from these equations were in good agreement with the experimental data.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Scientia Iranica - Volume 19, Issue 3, June 2012, Pages 619–625
نویسندگان
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