کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
416244 | 681311 | 2006 | 11 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Existence and uniqueness of relative incidence estimates in case-series analysis Existence and uniqueness of relative incidence estimates in case-series analysis](/preview/png/416244.png)
Case-series analysis is used to estimate relative incidences of clinical events in defined time intervals after vaccination compared to a control period. It has advantages, in terms of both a reduction in data collection effort, because it uses only data on cases, and a reduction in the resultant variances of estimates, due to individuals being self-controlled. The existence and uniqueness of relative incidence estimates in case-series analysis are investigated. For the relative incidence of a clinical event, a simple condition for existence and uniqueness of the estimate of the parameter vector in a case-series model is established. An algorithm is developed to examine the established condition, which provides a clue for remedy when the condition for existence and uniqueness is not satisfied.
Journal: Computational Statistics & Data Analysis - Volume 50, Issue 7, 1 April 2006, Pages 1807–1817