کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
416829 681404 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A new semiparametric estimation method for accelerated hazards mixture cure model
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نظریه محاسباتی و ریاضیات
پیش نمایش صفحه اول مقاله
A new semiparametric estimation method for accelerated hazards mixture cure model
چکیده انگلیسی

The semiparametric accelerated hazards mixture cure model provides a useful alternative to analyze survival data with a cure fraction if covariates of interest have a gradual effect on the hazard of uncured patients. However, the application of the model may be hindered by the computational intractability of its estimation method due to non-smooth estimating equations involved. We propose a new semiparametric estimation method based on a smooth estimating equation for the model and demonstrate that the new method makes the parameter estimation more tractable without loss of efficiency. The proposed method is used to fit the model to a SEER breast cancer data set.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computational Statistics & Data Analysis - Volume 59, March 2013, Pages 95–102
نویسندگان
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