کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
417706 681560 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interval estimation for response adaptive clinical trials
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نظریه محاسباتی و ریاضیات
پیش نمایش صفحه اول مقاله
Interval estimation for response adaptive clinical trials
چکیده انگلیسی

In this paper we examine a new method for constructing confidence intervals for the difference of success probabilities to analyze dependent data from response adaptive designs with binary responses. Specifically we investigate the feasibility of the Jeffreys–Perks procedure for interval estimation. Simulation results are derived to demonstrate the performance of the Jeffreys–Perks procedure compared with the profile likelihood method. It is found that both asymptotic methods perform well for small sample sizes despite being approximate procedures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computational Statistics & Data Analysis - Volume 55, Issue 1, 1 January 2011, Pages 725–730
نویسندگان
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