کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
421382 684211 2008 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparing bacterial genomes from linear orders of patterns
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نظریه محاسباتی و ریاضیات
پیش نمایش صفحه اول مقاله
Comparing bacterial genomes from linear orders of patterns
چکیده انگلیسی

We compare complete genomes from common words denoted MUMs for maximum unique matches. They allow to transform each genome into a linear order. We first evaluate the minimum length of a MUM shared by two genomes to be significant. Secondly, we compute maximal common chains of elements, that are in the same order in genomes. From these chains we define conserved genome segments as long DNA fragments having MUMs in the same order and with a bounded gap length between them. The resulting small number of segments allow to detect main evolutionary events as reversal or transposition of these fragments.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Discrete Applied Mathematics - Volume 156, Issue 8, 15 April 2008, Pages 1251–1262
نویسندگان
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