کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
423813 | 685292 | 2008 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A Process Model of Rho GTP-binding Proteins in the Context of Phagocytosis
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
نظریه محاسباتی و ریاضیات
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چکیده انگلیسی
At the early stages of the phagocytic signalling, Rho GTP-binding proteins play a key role. With the stimulus from the cell membrane and with the help from the regulators (GEF, GAP, Effector, GDI), these proteins serve as switches that interact with their environment in a complex manner. We present a generic process model for the Rho GTP-binding proteins, and compare it with a previous model that uses ordinary differential equations. We then extend the basic model to include the behaviour of the GDIs. We discuss the challenges this extension brings and directions of further research.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electronic Notes in Theoretical Computer Science - Volume 194, Issue 3, 20 January 2008, Pages 87-102
Journal: Electronic Notes in Theoretical Computer Science - Volume 194, Issue 3, 20 January 2008, Pages 87-102