کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
423813 685292 2008 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A Process Model of Rho GTP-binding Proteins in the Context of Phagocytosis
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نظریه محاسباتی و ریاضیات
پیش نمایش صفحه اول مقاله
A Process Model of Rho GTP-binding Proteins in the Context of Phagocytosis
چکیده انگلیسی

At the early stages of the phagocytic signalling, Rho GTP-binding proteins play a key role. With the stimulus from the cell membrane and with the help from the regulators (GEF, GAP, Effector, GDI), these proteins serve as switches that interact with their environment in a complex manner. We present a generic process model for the Rho GTP-binding proteins, and compare it with a previous model that uses ordinary differential equations. We then extend the basic model to include the behaviour of the GDIs. We discuss the challenges this extension brings and directions of further research.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electronic Notes in Theoretical Computer Science - Volume 194, Issue 3, 20 January 2008, Pages 87-102