کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4524085 | 1625425 | 2008 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A review of the behavioral and neurochemical consequences of early weaning in rodents
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
In mammals, mother-infant bonding is based on the dependence of the infant on the mother for sustenance, i.e., the infant suckles milk, but also involving a need for physical contact. Weaning is one of the most important events that occur in developing animals and the timing of natural weaning is dependent on environmental resources during the nursing period, i.e., if mothers rear their offspring under severe conditions, there is a trade-off between weaning at an earlier time, reducing offspring survival, and increased maternal survival. In the production of laboratory rodents offspring are routinely weaned earlier than in nature. Disruption of mother-infant bonding can induce physical and behavioral problems, including increased neuroendocrine stress responses, augmentation of fear and aggression, and reduced maternal behaviour. Here, we review the long-lasting effects of early weaning on adult rodent behavior and neuroendocrinology.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Animal Behaviour Science - Volume 110, Issues 1â2, March 2008, Pages 73-83
Journal: Applied Animal Behaviour Science - Volume 110, Issues 1â2, March 2008, Pages 73-83
نویسندگان
Takefumi Kikusui, Kayo Nakamura, Yuji Mori,