Recreating the seawater mixture composition of HOCs in toxicity tests with Artemia franciscana by passive dosing

► Passive dosing has some important benefits for the testing HOCs in aquatic media. ► P. dosing maintains constant exposure concentrations and gives higher reproducibility. ► P. dosing allows quantification of the salting out effect (for seawater toxicity assays). ► P. dosing can reproduce real mixtures of HOCs in toxicity tests (levels/proportions). ► P. dosing provides an approach for studying toxicity of environmental mixtures of HOCs.