Alteration of the kidney membrane proteome of Mizuhopecten yessoensis induced by low-level methyl parathion exposure

► The scallops Mizuhopecten yessoensis were exposed to low concentration of methyl parathion (MP). ► MP residues were significantly accumulated in the kidneys and the digestive glands of the scallops. ► 17 “membrane” proteins were differentially modulated in response to MP exposure. ► 12 differential proteins were further verified by quantitative PCR and western blotting. ► Mitochondrial processing peptidase is suggested as a potential biomarker for human health and environmental monitoring.