کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4530745 1324726 2008 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Xenoestrogen exposure and effects in English sole (Parophrys vetulus) from Puget Sound, WA
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم آبزیان
پیش نمایش صفحه اول مقاله
Xenoestrogen exposure and effects in English sole (Parophrys vetulus) from Puget Sound, WA
چکیده انگلیسی

Vitellogenin, a yolk protein produced in the liver of oviparous animals in response to estrogens, normally occurs only in sexually mature females with developing eggs. However, males can synthesize vitellogenin when exposed to environmental estrogens, making the abnormal production of vitellogenin in male animals a useful biomarker for xenoestrogen exposure. In 1997–2001, as part of the Washington State's Puget Sound Assessment and Monitoring Program, we surveyed English sole from a number of sites for evidence of xenoestrogen exposure, using vitellogenin production in males as an indicator. Significant levels of vitellogenin were found in male fish from several urban sites, with especially high numbers of fish affected in Elliott Bay, along the Seattle Waterfront. Intersex fish were rare, comprising only two fish out of more than 2900 examined. Other ovarian and testicular lesions, including oocyte atresia, were also observed, but their prevalence did not appear to be related to xenoestrogen exposure. However, at the Elliott Bay sites where abnormal vitellogenin production was observed in male sole, the timing of spawning in both male and female English sole appeared altered. Sources of xenoestrogens and types of xenoestrogens present in Elliott Bay are poorly documented, but the compounds are likely associated with industrial discharges, surface runoff, and combined sewer outfalls.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Aquatic Toxicology - Volume 88, Issue 1, 2 June 2008, Pages 29–38
نویسندگان
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