کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4545692 1626960 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Florida red tide toxins (brevetoxins) and longitudinal respiratory effects in asthmatics
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم آبزیان
پیش نمایش صفحه اول مقاله
Florida red tide toxins (brevetoxins) and longitudinal respiratory effects in asthmatics
چکیده انگلیسی

Having demonstrated significant and persistent adverse changes in pulmonary function for asthmatics after 1 h exposure to brevetoxins in Florida red tide (Karenia brevis bloom) aerosols, we assessed the possible longer term health effects in asthmatics from intermittent environmental exposure to brevetoxins over 7 years. 125 asthmatic subjects were assessed for their pulmonary function and reported symptoms before and after 1 h of environmental exposure to Florida red tide aerosols for up to 11 studies over seven years. As a group, the asthmatics came to the studies with normal standardized percent predicted pulmonary function values. The 38 asthmatics who participated in only one exposure study were more reactive compared to the 36 asthmatics who participated in ≥4 exposure studies. The 36 asthmatics participating in ≥4 exposure studies demonstrated no significant change in their standardized percent predicted pre-exposure pulmonary function over the 7 years of the study. These results indicate that stable asthmatics living in areas with intermittent Florida red tides do not exhibit chronic respiratory effects from intermittent environmental exposure to aerosolized brevetoxins over a 7 year period.

▶ Brevetoxins from Florida red tide (Karenia brevis bloom) can be aerosolized. ▶ Aerosolized brevetoxins can cause acute and subacute effects in asthmatics. ▶ Unstable asthmatics are particularly susceptible to aerosolized brevetoxin exposures. ▶ After 7 years of brevetoxin exposure, stable asthmatics have no chronic effects.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Harmful Algae - Volume 10, Issue 6, September 2011, Pages 744–748
نویسندگان
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