کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
467980 698149 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Physiologic insulin delivery with insulin feedback: A control systems perspective
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر علوم کامپیوتر (عمومی)
پیش نمایش صفحه اول مقاله
Physiologic insulin delivery with insulin feedback: A control systems perspective
چکیده انگلیسی

Individuals with type 1 diabetes mellitus must effectively manage glycemia to avoid acute and chronic complications related to aberrations of glucose levels. Because optimal diabetes management can be difficult to achieve and burdensome, research into a closed-loop insulin delivery system has been of interest for several decades. This paper provides an overview, from a control systems perspective, of the research and development effort of a particular algorithm—the external physiologic insulin delivery system. In particular the introduction of insulin feedback, based on β-cell physiology, is covered in detail. A summary of human clinical trials is provided in the context of the evolution of this algorithm, and this paper outlines some of the research avenues that show particular promise.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computer Methods and Programs in Biomedicine - Volume 102, Issue 2, May 2011, Pages 130–137
نویسندگان
,