کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
481907 1446192 2007 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modeling gene regulatory networks with piecewise linear differential equations
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر علوم کامپیوتر (عمومی)
پیش نمایش صفحه اول مقاله
Modeling gene regulatory networks with piecewise linear differential equations
چکیده انگلیسی

Microarray chips generate large amounts of data about a cell’s state. In our work we want to analyze these data in order to describe the regulation processes within a cell. Therefore, we build a model which is capable of capturing the most relevant regulating interactions and present an approach how to calculate the parameters for the model from time-series data. This approach uses the discrete approximation method of least squares to solve a data fitting modeling problem. Furthermore, we analyze the features of our proposed system, i.e., which kinds of dynamical behaviors the system is able to show.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Operational Research - Volume 181, Issue 3, 16 September 2007, Pages 1148–1165
نویسندگان
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