کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
487375 703572 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Promoter Sequence Analysis through No Gap Multiple Sequence Alignment of Motif Pairs
ترجمه فارسی عنوان
تجزیه و تحلیل توالی پیوسته از طریق بدون انحراف چند ترتیب صاف مات؟
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر علوم کامپیوتر (عمومی)
چکیده انگلیسی

The advancement in the sequencing technology has led to exponential increase in the biological sequence data. Therefore the need for methods and techniques that analyze this sequence data are in demand. A central task in analysis of this data is sequence alignment. In this work, we present a new multiple sequence alignment method for analyzing the similarity/homology existing in the promoter sequences. We extract the motif pair feature from the binarized position specific motif matrix (PSMM) of each promoter pair or sets. We then compare the count of motif pairs between the promoter sequences to find the similarity. The efficacy of the proposed method is tested on two datasets obtained from NCBI. The results obtained agree with our understanding of organism similarity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Procedia Computer Science - Volume 58, 2015, Pages 356-362