Characteristics of Displacement Data Due to Time Scale for the Combination of Brownian Motion with Intermittent Adsorption

Single-molecule tracking data near solid surfaces contains information on diffusion that is potentially affected by adsorption. However, molecular adsorption can occur in an intermittent manner, and the overall phenomenon is regarded as slower yet normal diffusion if the time scale of each adsorption event is sufficiently shorter than the interval of data acquisition. We compare simple numerical model systems that vary in the time scale of adsorption event while sharing the same diffusion coefficient, and show that the shape of the displacement distribution depends on the time resolution. We also evaluate the characteristics by statistical quantities related to the large deviation principle.