Original articleReaction of aryne with aza-Morita-Baylis-Hillman adducts: Synthesis of 4-quinolones and N-arylation products

The reaction of aryne with aza-Morita-Baylis-Hillman (aza-MBH) adducts has been studied. Aryne reacts with aza-MBH adducts through a cascade insertion-cyclization-ene reaction to produce 4-quinolones in 18-44% yields; meanwhile, aza-MBH adducts undergo N-insertion reaction with aryne to afford N-arylation products in 27-77% yields.