کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4909383 | 1362618 | 2017 | 9 صفحه PDF | دانلود رایگان |
A simple and facile one-pot three-component synthesis of 5-substituted 1H-tetrazole derivatives from aldehydes catalyzed by doped nano-sized Cu2O on melamine-formaldehyde resin (nano-Cu2O-MFR) is described. In this protocol, treatment of structurally diverse aldehydes, hydroxylamine hydrochloride and tetrabutylammonium azide (TBAA) as an azide source in the presence of nano-Cu2O-MFR as an efficient heterogeneous nano-catalyst affords the corresponding 5-substituted 1H-tetrazoles in good to excellent yields. The influence of different parameters on the progress of reaction was studied. The nano-Cu2O-MFR is a cheap and stable nano-catalyst that could be easily prepared, recycled and reused for many consecutive reaction runs without significant decrease in its activity.
Journal: Journal of Saudi Chemical Society - Volume 21, Issue 2, February 2017, Pages 220-228