Simulation study of rare cell trajectories and capture rate in periodic obstacle arrays

We vary two parameters - hematocrit and column radius of the cylindrical obstacles. While the hematocrit has a slight influence on the CTC trajectories and the cell capture rate computed by the newly developed model, the effect of column radius is much more pronounced. We observe that increase in column radius increases the capture rate quadratically. And secondly, with the exception of the very small column radius, increase in hematocrit slightly decreases the capture rate linearly.