Virtual Clinical Trials: A tool for the Study of Transmission of Nosocomial Infections

A clinical trial is a study designed to demonstrate the efficacy and safety of a drug, procedure, medical device, or diagnostic test. Since clinical trials involve research in humans, they must be carefully designed and must comply strictly with a set of ethical conditions. Logistical disadvantages, ethical constraints, costs and high execution times could have a negative impact on the execution of the clinical trial. This article proposes the use of a simulation tool, the MRSA-T-Simulator, to design and perform “virtual clinical trials” for the purpose of studying MRSA contact transmission among hospitalized patients. The main advantage of the simulator is its flexibility when it comes to configuring the patient population, healthcare staff and the simulation environment.