کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5009101 | 1462039 | 2017 | 8 صفحه PDF | دانلود رایگان |
- Small-sized AgNPs uniformly deposited SDS functionalized carbon nanotube.
- Fabricated a novel non-enzymatic O2â sensor based on AgNPs/SDS-MWCNTs/GCE.
- A remarkable low detection limit of 8.97Â ÃÂ 10â11Â M was achieved.
- The sensor can measure the release of O2â from living cells directly, and is AA dose-dependent manner.
Considering the crucial roles of superoxide anion (O2â) in pathological conditions, it is of great urgency to establish a reliable approach for real-time determination of O2â. Herein, a sensitive non-enzymatic sensor was constructed based on silver nanoparticles (AgNPs) and sodium dodecyl sulfate functionalized carbon nanotubes (SDS-MWCNTs) composites to measure the release of O2â from living cells. As an analytical and sensing platform, the AgNPs/SDS-MWCNTs modified glassy carbon electrode exhibited excellent electrochemical performance toward O2â with a determination limit as low as 0.0897Â nM and wide linear range of 6 orders of magnitude, which was superior to other O2â electrochemical sensors. The excellent performance was attributed to the SDS-MWCNTs composites being used as effective load matrix for the deposition of AgNPs. Importantly, this novel non-enzymatic sensor could be applied to determination of O2â released from living cells, and the amount of flux of O2â increased accordingly with the improving of the concentration of AA, which has the possibility of application in clinical diagnostics to assess oxidative stress of living cells.
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Journal: Sensors and Actuators B: Chemical - Volume 252, November 2017, Pages 503-510