کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5009595 | 1462051 | 2017 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Label free ultrasensitive optical sensor decorated with polyaniline nanofibers: Characterization and immunosensing application
ترجمه فارسی عنوان
سنسور نوری فوق حساس بدون برچسب، تزئین شده با نانو فیبرهای پلی آنیلین: کاربرد و کاربرد ایمن سازی
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Conducting polymers have been studied for decades, and the use of such polymers in sensing applications has been explored extensively. Most of these have exploited the fact that protonation or de-protonation of these polymers, have an effect on their conductivity and conformational structure. We demonstrate a phenomenon, i.e. changes to the spectroscopic properties of conducting polymer polyaniline (PAni), without explicit protonation or de-protonation, due to immunological interactions happening on the surface. To explore the reason behind these spectroscopic changes, PAni was analyzed using Hydrogen Nuclear Magnetic Resonance (HNMR), and Fourier Transformed Infrared (FTIR) spectroscopy. It was further characterized using Scanning Electron Microscope (SEM) imaging and Selected Area Electron Diffraction (SAED). These optical alterations of polyaniline have been utilized to develop a simple, cost effective, yet highly sensitive immunosensor. Human Immunoglobulin G (HIgG) was immobilized on the polyaniline coated fiber-optic probe using cross linker molecules, and goat anti-Human Immunoglobulin G (GaHIgG) was used as the analyte. This study fundamentally utilizes optical properties of PAni to develop a simple immunosensor which is able to detect analyte concentrations as low as 37Â pM.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 240, March 2017, Pages 443-450
Journal: Sensors and Actuators B: Chemical - Volume 240, March 2017, Pages 443-450
نویسندگان
Sutapa Chandra, Reshma Bharadwaj, Soumyo Mukherji,