کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
504033 864261 2015 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Atlas-based liver segmentation and hepatic fat-fraction assessment for clinical trials
ترجمه فارسی عنوان
تجزیه و تحلیل کبد مبتنی بر اطلس و ارزیابی فراوانی کبد کبدی برای آزمایشات بالینی
کلمات کلیدی
ارزیابی کسر چربی کبد، تقسیم بندی، مدل قابل انطباق، اطلس آماری
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نرم افزارهای علوم کامپیوتر
چکیده انگلیسی

Automated assessment of hepatic fat-fraction is clinically important. A robust and precise segmentation would enable accurate, objective and consistent measurement of hepatic fat-fraction for disease quantification, therapy monitoring and drug development. However, segmenting the liver in clinical trials is a challenging task due to the variability of liver anatomy as well as the diverse sources the images were acquired from. In this paper, we propose an automated and robust framework for liver segmentation and assessment. It uses single statistical atlas registration to initialize a robust deformable model to obtain fine segmentation. Fat-fraction map is computed by using chemical shift based method in the delineated region of liver. This proposed method is validated on 14 abdominal magnetic resonance (MR) volumetric scans. The qualitative and quantitative comparisons show that our proposed method can achieve better segmentation accuracy with less variance comparing with two other atlas-based methods. Experimental results demonstrate the promises of our assessment framework.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computerized Medical Imaging and Graphics - Volume 41, April 2015, Pages 80–92
نویسندگان
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