کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
504143 864273 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Extraction of time activity curves from gated FDG-PET images for small animals’ heart studies
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نرم افزارهای علوم کامپیوتر
پیش نمایش صفحه اول مقاله
Extraction of time activity curves from gated FDG-PET images for small animals’ heart studies
چکیده انگلیسی

We introduce a new approach to extract the input function and the tissue time activity curve from dynamic ECG-gated 18F-FDG PET images. These curves are mandatory to model the myocardium metabolic rate of glucose for heart studies. The proposed method utilizes coupled active contours to track the myocardium and the blood pool deformations. Furthermore, a statistical approach is developed to model the blood and tissue activities and to correct for spillovers. The developed algorithm offers a reliable alternative to serial blood sampling for small animal cardiac PET studies. Indeed, the calculated MMRG value differs by 1.54% only from the reference value.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computerized Medical Imaging and Graphics - Volume 36, Issue 6, September 2012, Pages 484–491
نویسندگان
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