Extraocular muscle quantification using mathematical morphology: A semi-automatic method for analyzing muscle enlargement in orbital diseases

Mathematical morphology was used to quantify the dimensions of the human extraocular muscles in computed tomography orbital scans. Coronal images of 28 patients with Graves orbitopathy and 5 controls (218 orbital scans) were analyzed with an algorithm for extraocular muscle segmentation. The results showed that measurements of extraocular muscle area obtained with semi-automatic segmentation are highly correlated with manual tracing and provides a simple method to quantify orbital structures including the extraocular muscles.