کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
505396 864499 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fractal-like correlations of the fluctuating inter-spike membrane potential of a Helix aspersa pacemaker neuron
ترجمه فارسی عنوان
همبستگی های فراکتال از پتانسیل غشاء بین پره های نوسان کننده یک نورون ضربان قلب اسپرین
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نرم افزارهای علوم کامپیوتر
چکیده انگلیسی


• We found long-term correlations in pacemaker neural inter-spike voltage fluctuations.
• Such behavior is probably linked to mechanisms that regulate the membrane potential.
• Our study endorses critical-like phenomena occurring at a single-neuron level.

We analyzed the voltage fluctuations of the membrane potential manifested along the inter-spike segment of a pacemaker neuron. Time series of intracellular inter-spike voltage fluctuations were obtained in the current-clamp configuration from the F1 neuron of 12 Helix aspersa specimens. To assess the dynamic or stochastic nature of the voltage fluctuations these series were analyzed by Detrended Fluctuation Analysis (DFA), providing the scaling exponent α. The median α result obtained for the inter-spike segments was 0.971 ([0.963, 0.995] lower and upper quartiles). Our results indicate a critical-like dynamic behavior in the inter-spike membrane potential that, far from being random, shows long-term correlations probably linked to the dynamics of the mechanisms involved in the regulation of the membrane potential, thereby endorsing the occurrence of critical-like phenomena at a single-neuron level.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computers in Biology and Medicine - Volume 53, 1 October 2014, Pages 258–264
نویسندگان
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