Multi-agent systems simulating the physiological role of plasmic membrane

This paper presents our multi-agent framework for modelling and simulating the physiological role of plasmic membrane specially the ‘endocytosis by receptors’ and the ‘exocytosis’ mechanisms.As the dysfunction of a plasmic membrane may cause several illnesses (the family hypercholesterolemia, the dilation and the permeability of blood vessel, the allergic reactions as the asthma, rums of hays, hives, etc.), the objective of our multi-agent framework is to be a virtual world of cellular and molecular biology while simulating the physiological role of plasmic membrane in order to help its specialists to better understand, to good interpret and to warn changes of cell interaction and cell adaptation with its environment via its plasmic membrane.The architecture of our multi-agent framework is composed of a set of reactive agents. These agents use an ontology (named OntoCell) to communicate and to represent their knowledge. OntoCell describes the knowledge of cellular biology.Our framework is implemented with a multi-agent platform (named DIMA).