Understanding velocity of sound in trabecular bone via computer simulations

Osteoporosis is a condition characterized by low bone mass and micro-architectural deterioration leading to non-traumatic fractures of the skeleton. It is a potentially debilitating condition especially for senior citizens. There is growing interest for quantitative ultrasound to measure bone mineral density. However, understanding of ultrasound–bone interaction is limited. Simulating ultrasound propagation of bone can help us better understand ultrasound–bone interaction and provide insight into bone architecture. In this study a mathematical model for the propagation of sound in bone is presented. Results demonstrate the suitability of the proposed modeling approach and the model's capability to reproduce conditions in the lab.