کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
506200 864585 2006 19 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ONTOFUSION: Ontology-based integration of genomic and clinical databases
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نرم افزارهای علوم کامپیوتر
پیش نمایش صفحه اول مقاله
ONTOFUSION: Ontology-based integration of genomic and clinical databases
چکیده انگلیسی

ONTOFUSION is an ontology-based system designed for biomedical database integration. It is based on two processes: mapping and unification. Mapping is a semi-automated process that uses ontologies to link a database schema with a conceptual framework—named virtual schema. There are three methodologies for creating virtual schemas, according to the origin of the domain ontology used: (1) top-down—e.g. using an existing ontology, such as the UMLS or Gene Ontology—, (2) bottom-up—building a new domain ontology— and (3) a hybrid combination. Unification is an automated process for integrating ontologies and hence the database to which they are linked. Using these methods, we employed ONTOFUSION to integrate a large number of public genomic and clinical databases, as well as biomedical ontologies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computers in Biology and Medicine - Volume 36, Issues 7–8, July–August 2006, Pages 712–730
نویسندگان
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