Synthesis and characterization of a series of novel 2-Schiff base-substituted phenylpyrimidine

A new series of pyrimidine derivatives containing Schiff bases structure have been synthesized efficiently by modification of the C-2 position of Biginelli 3,4-dihydropyrimidin-2-(1H)-thiones (DHPMs). Their structures have been characterized by IR, 1H NMR, 13C NMR, MS spectra and elemental analysis.