کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5142316 1496024 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Predictive values of some atherogenic risk factors in young workers occupationally exposed to vinyl chloride and heavy metals
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Predictive values of some atherogenic risk factors in young workers occupationally exposed to vinyl chloride and heavy metals
چکیده انگلیسی
Traditional risk factors do not explain all of the risk for incident coronary heart disease (CHD) events. Human susceptibility to atherosclerosis and consequently coronary heart disease is maximally exhibited when the environment is unfavorable, especially in workplace. Thus, the present work was undertaken to study the relation of lipoprotein (a) to the other atherogenic risk factors in young workers occupationally exposed to vinyl chloride or some heavy metals by studying the effect of exposure to these agents on the lipid profiles, immunological parameters and the antioxidant defense enzyme system. The results of this study revealed that, in metalists, the cluster features of dyslipidemia, impairment in antioxidant defense mechanism and high levels of Lp (a), CICs, C3 and C4 represent unfortunate events on their cardiovascular system. In VCW, vinyl chloride metabolites caused severe oxidative stress reflected by impairment in the antioxidant defense accompanied by propagation of lipid peroxidation. Additionally, the elevated levels of Lp (a), CICs, C3 and C4 may point out to their role as atherogenic risk factors in those workers. In conclusion, young workers occupationally exposed to VC may be at high risk of developing cardiovascular disease in spite of having normolipidemia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Arabian Journal of Chemistry - Volume 10, Issue 1, January 2017, Pages 100-108
نویسندگان
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