کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5142437 1496027 2016 24 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antibacterial susceptibility of new copper(II) N-pyruvoyl anthranilate complexes against marine bacterial strains - In search of new antibiofouling candidate
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Antibacterial susceptibility of new copper(II) N-pyruvoyl anthranilate complexes against marine bacterial strains - In search of new antibiofouling candidate
چکیده انگلیسی
Biofouling is a serious problem and very difficult to overcome, since the marine biofilm-producing microorganisms resist the host defense mechanism and antibiotic therapy. Therefore, there is an urgent need to develop potent anti-biofouling agent to effectively eradicate unwanted biofilms. Our work represents antibacterial susceptibility and antibiofilm forming assay of new copper(II) N-pyruvoyl anthranilate architectures (4a-d) against Staphylococcus aureus and Escherichia coli, marine isolates. The preliminary biofilm susceptibility tests revealed that, the most potent staphylococcalcidal (MIC/MBC = 9.25/10.50 mM) and E. coli-cidal (MIC/MBC = 13.25/13.50 mM) agent, 4d, exhibits significant biofilm inhibition. Complex 4d can therefore provide an antibiofilm-forming agent candidate to curb the formation of biofilms.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Arabian Journal of Chemistry - Volume 9, Issue 6, November 2016, Pages 825-834
نویسندگان
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