کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5142437 | 1496027 | 2016 | 24 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antibacterial susceptibility of new copper(II) N-pyruvoyl anthranilate complexes against marine bacterial strains - In search of new antibiofouling candidate
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
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چکیده انگلیسی
Biofouling is a serious problem and very difficult to overcome, since the marine biofilm-producing microorganisms resist the host defense mechanism and antibiotic therapy. Therefore, there is an urgent need to develop potent anti-biofouling agent to effectively eradicate unwanted biofilms. Our work represents antibacterial susceptibility and antibiofilm forming assay of new copper(II) N-pyruvoyl anthranilate architectures (4a-d) against Staphylococcus aureus and Escherichia coli, marine isolates. The preliminary biofilm susceptibility tests revealed that, the most potent staphylococcalcidal (MIC/MBCÂ =Â 9.25/10.50Â mM) and E. coli-cidal (MIC/MBCÂ =Â 13.25/13.50Â mM) agent, 4d, exhibits significant biofilm inhibition. Complex 4d can therefore provide an antibiofilm-forming agent candidate to curb the formation of biofilms.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Arabian Journal of Chemistry - Volume 9, Issue 6, November 2016, Pages 825-834
Journal: Arabian Journal of Chemistry - Volume 9, Issue 6, November 2016, Pages 825-834
نویسندگان
Reda F.M. Elshaarawy, Christoph Janiak,