کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5142493 | 1496034 | 2016 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and antibacterial studies of 2-aryl-3-alkanamido-4H-thiazolidin-4-one derivatives
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and antibacterial studies of 2-aryl-3-alkanamido-4H-thiazolidin-4-one derivatives Synthesis and antibacterial studies of 2-aryl-3-alkanamido-4H-thiazolidin-4-one derivatives](/preview/png/5142493.png)
چکیده انگلیسی
A series of 2-aryl-3-alkanamido-4H-thiazolidin-4-ones were synthesized from long chain fatty acid hydrazides and studied for their in vitro antibacterial activity. Long chain fatty acid hydrazides 1 on reaction with different aromatic aldehydes in the presence of catalytic amount of glacial acetic acid yielded the corresponding aryl hydrazones 2 which on further reaction with thioglycolic acid in the presence of anhydrous zinc chloride furnished the title compounds 3. These compounds were characterized by CHN analyses, IR, mass and 1H NMR spectral data. All the compounds were evaluated for their in vitro antibacterial activity against two Gram positive strains (Bacillus subtilis and Staphylococcus aureus) and two Gram negative strains (Escherichia coli and Pseudomonas aeruginosa) and their minimum inhibitory concentration (MIC) were determined.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Arabian Journal of Chemistry - Volume 9, Supplement 1, September 2016, Pages S290-S295
Journal: Arabian Journal of Chemistry - Volume 9, Supplement 1, September 2016, Pages S290-S295
نویسندگان
Sandeep Jain, Ashwani Kumar, Mahesh Kumar, Neelam Jain,