Greener organic solvents in analytical chemistry

The paper presents the most recent advances in analytical applications of greener organic solvents. Substitution of problematic solvents with more benign organic ones is much easier than shifting to technique applying alternative solvents, such as ionic liquids or supercritical fluids. In the area of liquid chromatography greener mobile phases, much attention is given to application ethanol or acetone instead of acetonitrile. Solvent-based extractions more often include the application of bio-based organic solvents, such as esters, alcohols or terpenes. All solvents applied in analytical sciences should be carefully assessed before their application.