Potential anti-cancer activity of a novel Bi(III) containing thiosemicarbazone derivative

By mixing 5-bromo-2-furaldehyde, phenylthiosemicarbazide and Bi(CH3COO)3, a new amorphous bismuth-containing complex was synthesized under aqueous conditions via a one-pot method, which effectively inhibited the proliferation and migration of A549 and H460 lung cancer cells, induced cell apoptosis and displayed fairly low cytotoxicity to normal human lung fibroblast (HLF), indicative of great potential anti-cancer activity.