Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling

Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 127, 15 February 2017, Pages 703-714

Fabien Plisson, Timothy A. Hill, Justin M. Mitchell, Huy N. Hoang, Aline D. de Araujo, Weijun Xu, Adam Cotterell, David J. Edmonds, Robert V. Stanton, David R. Derksen, Paula M. Loria, David A. Griffith, David A. Price, Spiros Liras, David P. Fairlie,