کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5485282 | 1523187 | 2018 | 25 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Real-time ultrasound angiography using superharmonic dual-frequency (2.25Â MHz/30Â MHz) cylindrical array: In vitro study
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موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Recent studies suggest that dual-frequency intravascular ultrasound (IVUS) transducers allow detection of superharmonic bubble signatures, enabling acoustic angiography for microvascular and molecular imaging. In this paper, a dual-frequency IVUS cylindrical array transducer was developed for real-time superharmonic imaging. A reduced form-factor lateral mode transmitter (2.25 MHz) was used to excite microbubbles effectively at 782 kPa with single-cycle excitation while still maintaining the small size and low profile (5 Fr) (3 Fr = 1 mm) for intravascular imaging applications. Superharmonic microbubble responses generated in simulated microvessels were captured by the high frequency receiver (30 MHz). The axial and lateral full-width half-maximum of microbubbles in a 200-μm-diameter cellulose tube were measured to be 162 μm and 1039 μm, respectively, with a contrast-to-noise ratio (CNR) of 16.6 dB. Compared to our previously reported single-element IVUS transducers, this IVUS array design achieves a higher CNR (16.6 dB vs 11 dB) and improved axial resolution (162 μm vs 616 μm). The results show that this dual-frequency IVUS array transducer with a lateral-mode transmitter can fulfill the native design requirement (â¼3-5 Fr) for acoustic angiography by generating nonlinear microbubble responses as well as detecting their superharmonic responses in a 5 Fr form factor.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasonics - Volume 82, January 2018, Pages 298-303
Journal: Ultrasonics - Volume 82, January 2018, Pages 298-303
نویسندگان
Zhuochen Wang, K. Heath Martin, Paul A. Dayton, Xiaoning Jiang,