کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5491039 1524789 2017 8 صفحه PDF سفارش دهید دانلود رایگان
عنوان انگلیسی مقاله ISI
A method for increasing the homogeneity of the temperature distribution during magnetic fluid hyperthermia with a Fe-Cr-Nb-B alloy in the presence of blood vessels
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
سفارش ترجمه تخصصی
با تضمین قیمت و کیفیت
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
A method for increasing the homogeneity of the temperature distribution during magnetic fluid hyperthermia with a Fe-Cr-Nb-B alloy in the presence of blood vessels
چکیده انگلیسی
Magnetic hyperthermia ablates tumor cells by absorbing the thermal energy from magnetic nanoparticles (MNPs) under an external alternating magnetic field. The blood vessels (BVs) within tumor region can generally reduce treatment effectiveness due to the cooling effect of blood flow. This paper aims to investigate the cooling effect of BVs on the temperature field of malignant tumor regions using a complex geometric model and numerical simulation. For deriving the model, the Navier-Stokes equation for blood flow is combined with Pennes bio-heat transfer equation for human tissue. The effects on treatment temperature caused by two different BV distributions inside a mammary tumor are analyzed through numerical simulation under different conditions of flow rate considering a Fe-Cr-Nb-B alloy, which has low Curie temperature ranging from 42 °C to 45 °C. Numerical results show that the multi-vessel system has more obvious cooling effects than the single vessel one on the temperature field distribution for hyperthermia. Besides, simulation results show that the temperature field within tumor area can also be influenced by the velocity and diameter of BVs. To minimize the cooling effect, this article proposes a treatment method based on the increase of the thermal energy provided to MNPs associated with the adoption of low Curie temperature particles recently reported in literature. Results demonstrate that this approach noticeably improves the uniformity of the temperature field, and shortens the treatment time in a Fe-Cr-Nb-B system, thus reducing the side effects to the patient.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetism and Magnetic Materials - Volume 432, 15 June 2017, Pages 330-335
نویسندگان
, , ,
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
سفارش ترجمه تخصصی
با تضمین قیمت و کیفیت