کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5497027 1399880 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Methylation effect on the ohmic resistance of a poly-GC DNA-like chain
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک و نجوم (عمومی)
پیش نمایش صفحه اول مقاله
Methylation effect on the ohmic resistance of a poly-GC DNA-like chain
چکیده انگلیسی
We determine, by using a tight-binding model Hamiltonian, the characteristic current-voltage (IxV) curves of a 5-methylated cytosine single strand poly-GC DNA-like finite segment, considering the methyl groups attached laterally to a random fraction of the cytosine basis. Striking, we found that the methylation significantly impacts the ohmic resistance (R) of the DNA-like segments, indicating that measurements of R can be used as a biosensor tool to probe the presence of anomalous methylation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physics Letters A - Volume 380, Issue 42, 14 October 2016, Pages 3559-3563
نویسندگان
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