More than meets the eye: Searching for additional findings in primary brain calcification

- Primary familial brain calcification (PFBC) has diverse presentations
- Impairment beyond the brain has been described in PFBC patients
- Findings emphasized here include elevated CSF-Pi and white matter hyperintensities
- Such alternative medical findings appear as potential biomarkers for PFBC diagnosis
- Combined, study findings reinforce the necessity of further systemic studies on PFBC