کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5524896 1401457 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The burden of oesophageal cancer in Central and South America
ترجمه فارسی عنوان
بار ناشی از سرطان پستان در آمریکای مرکزی و جنوبی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی


- Oesophageal cancer represents major public health problem in the Southern Cone of South America.
- Males are more frequently affected than females.
- Oesophageal squamous cell carcinoma is the most frequent diagnosis.
- Incidence and mortality trends seem to decline in Argentina, Chile, Brazil (incidence), Costa Rica.
- Continuous monitoring of rates may provide the basis for cancer prevention and control.

Rationale and objectiveOesophageal cancer shows marked geographic variations and is one of the leading causes of cancer death worldwide. We described the burden of this malignancy in Central and South America.MethodsRegional and national level incidence data were obtained from 48 population-based cancer registries in 13 countries. Mortality data were obtained from the WHO mortality database. Incidence of oesophageal cancer by histological subtype were available from high-quality population-based cancer registries.ResultsMales had higher incidence and mortality rates than females (male-to-female ratios: 2-6:1 and 2-5:1). In 2003-2007, the highest rates were in Brazil, Uruguay, Argentina and Chile. Mortality rates followed the incidence patterns. Incidence of oesophageal squamous cell carcinoma (SCC) was higher than adenocarcinoma (AC), except in females from Cuenca (Ecuador). SCC and AC incidence were higher in males than females, except in the Region of Antofagasta and Valdivia (Chile), Manizales (Colombia) and Cuenca (Ecuador). Incidence and mortality rates tended to decline in Argentina, Chile, Brazil (incidence) and Costa Rica from 1997 to 2008.ConclusionThe geographic variation and sex disparity in oesophageal cancer across Central and South America may reflect differences in the prevalence of tobacco smoking and alcohol consumption which highlights the need to implement and/or strengthen tobacco and alcohol control policies. Maté consumption, obesity, diet and Helicobacter pylori infection may also explain the variation in oesophageal cancer rates but these relationships should be evaluated. Continuous monitoring of oesophageal cancer rates is necessary to provide the basis for cancer prevention and control in the region.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Epidemiology - Volume 44, Supplement 1, September 2016, Pages S53-S61
نویسندگان
, , , ,