کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5524901 1401457 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The burden of cutaneous melanoma and status of preventive measures in Central and South America
ترجمه فارسی عنوان
بار ناشی از ملانوم پوستی و وضعیت اقدامات پیشگیرانه در آمریکای مرکزی و آمریکای جنوبی؟
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی


- Incidence rates were, on average, lower in Central than in South American countries.
- Age-standardized incidence rates were between 1 and 5 per 100,000.
- Men had higher proportions of melanomas on the trunk, women on their limbs.
- Melanomas of the acral type are common, representing at least 4-15% of cases.
- Several countries have started national or regional activities for skin cancer prevention

Rationale and objectiveVery little is known about the burden of cutaneous melanoma in Central and South America, despite the existence of a reasonable amount of population-based data. We present data on melanoma incidence calculated in a standardized way for Central and South America, as well as an overview of primary and secondary prevention issues in the region.MethodsCancer registry data on all incident cases reported in the different registries present in Central and South America were combined to provide registry-based country estimates of age-standardized, sex-specific cutaneous melanoma incidence overall, and by histological subtype and anatomical site. A literature search provided additional information.ResultsAge-standardized incidence rates were between 1 and 5 per 100,000 and tended to be higher further away from the equator. Cutaneous melanomas of the acral type, mostly occurring on the lower limbs, are a distinguishing feature of melanoma in Central and South America in comparison with high-incidence areas. Several preventive measures, both primary and secondary, are in place, albeit largely without evaluation.ConclusionDue to incomplete registration and different registration practices, reliable and comparable data on melanoma were difficult to obtain; thus it is likely that the true burden of melanoma in Central and South America has been underestimated. The different characteristics of the cutaneous melanoma patient population in terms of anatomical site and histological type distribution imply a need for adapted primary and secondary prevention measures. The generally high ambient ultraviolet radiation levels require sufficient sun protection measures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Epidemiology - Volume 44, Supplement 1, September 2016, Pages S100-S109
نویسندگان
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