CASE REPORTMicrosporidial Keratoconjunctivitis in a Pet Bearded Dragon (Pogona vitticeps)

A 4-month-old female bearded dragon (Pogona vitticeps) was presented with unilateral conjunctivitis. The conjunctivitis was not responsive to topical antibiotic or anti-inflammatory therapy and continued to progress in severity. Conjunctival tissue was sampled and microsporidial conjunctivitis was diagnosed on histopathological evaluation of submitted samples. Medical therapy was initiated and included topical itraconazole, systemic itraconazole, and systemic fenbendazole. Serial serum chemistry panels and complete blood counts were monitored for potential side effects associated with the medications. Despite treatment, the conjunctivitis progressed and enucleation was performed. Histopathology on the enucleated globe confirmed the diagnosis of microsporidial keratoconjunctivitis. Systemic itraconazole was administered at 5 mg/kg orally for approximately 3 months. No abnormalities were detected on hematologic diagnostic testing during the treatment period. A computed tomographic scan was performed to monitor for systemic lesions, but no abnormalities were detected. About 12 months after initial presentation, the bearded dragon is healthy and there are no overt signs of disease.