کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5594134 1571286 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bifurcation of the respiratory response to lung inflation in anesthetized dogs
ترجمه فارسی عنوان
تقسیم پاسخ تنفسی به تورم ریه در سگهای بیهوشی
کلمات کلیدی
تنفس، خاموش سوئیچ خروجی، رفلکس واگ،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
چکیده انگلیسی
Numerous studies have demonstrated the effect of lung volume on prolongation of duration of expiration (TE) with limited understanding of the TE shortening and termination of expiration as observed in newborn. In 14 dogs, the effects of varied onset of lung inflation during expiration on the TE were evaluated. When lung inflation was applied in the first part of expiration (20-60% of TE) TE was lengthened. However, in the second portion (60-80% of TE) of expiration, lung inflation either terminated or prolonged TE; whereas in the last portion of expiration (80-90% of TE), lung inflation tended to terminate expiration prematurely. The effects were abolished after bilateral vagotomy. We postulate that prolongation of TE relates to the Breuer-Hering inflation reflex, which increases the time needed for a passive expiration; whereas the ability to shorten TE could relate to Head's paradoxical reflex acting to initiate inspiration or to activate inspiratory motor activity to brake expiratory flow as occurs in the newborn.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 244, October 2017, Pages 26-31
نویسندگان
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